Résumé

Curriculum Vitae for Luke A. D. Hutchison
PhD in computer science and computational biology,
MIT CSAIL (in collaboration with Harvard Medical School)
TED Fellow, Long Beach 2011

See also my LinkedIn public profile.


Summary

I completed a PhD in Computer Science and Computational Biology at MIT CSAIL in collaboration with Harvard Medical School.  For my thesis research I searched for genomic regulators of cell phenotype.  I am passionate about algorithms, machine learning, both computer and human languages, and the power of information to change society.  I have been programming and/or building circuits and gadgets my whole life. I am a TED Fellow.


Work History


Senior Research Scientist / Deep Learning Researcher, Google Accelerated Science; Google Machine Intelligence, Oct 2012 - Oct 2016
  • On the Google Accelerated Science team, applied novel deep learning techniques to accelerate computational chemistry. I was able to accelerate quantum chemistry calculations by up to 7 orders of magnitude with high accuracy using a trained machine learning model, which will allow chemists and material scientists to explore a much larger area of the chemical space for compounds with interesting properties.
  • Also worked as Tech Lead on Ray Kurzweil's Artificial Intelligence project; was recruited directly by Ray to found his AI team. Responsibilities included meeting with heads of major product areas throughout Google to determine how to optimally add AI capabilities to current and future Google products, and growing the team from scratch to 30+ engineers. Also led an effort to apply unsupervised learning to the problem of inferring the structure of language from the statistical patterns of language usage across all text on the Web. Involved technical design of Natural Language Processing technologies, implementation of novel algorithms for parsing and semantic modeling, reverse-engineering of human cognition and experimentation to reconstruct human cognition in software.
VP of Data Science, RentLogic, 2015 - present
  • Statistical analysis and publication of large civic housing datasets from New York City for easy access (including complaints, violations and litigation data sources) to disrupt slumlord corruption in the housing rental market, by providing data transparency to tenants.
Senior Principal Scientist, Quanttus, June 2014 - Feb 2015
  • Biometric signal processing; code optimization for embedded systems; designing population-level data analysis strategy
Postdoctoral Fellow, Harvard Medical School (Isaac "Zak" Kohane lab), May 2011 - Aug 2012
  • Integrative genomics study of cell division and tissue differentiation in C. elegans 
Research Assistant, MIT CSAIL (Berger Lab) in collaboration with Harvard Medical School (Zak Kohane Lab), Sept 2006 - Apr 2011
  • Integrative genomics study of cell division and tissue differentiation in C. elegans 
Internship, Google, summer 2007 (Google Book Search team)
  • Responsibilities: Development of a large distributed Naïve Bayes clustering algorithm in C++ that predicted subject code from metadata and content of millions of books. 
Director of Bioinformatics, the Sorenson Molecular Genealogy Foundation (smgf.org), 2004-2005
  • Responsibilities: Development of new software algorithms for population genetics and analysis of DNA and genealogical data, including phylogeny, clustering, fuzzy matching of genealogical data, data mining, pattern recognition, DNA sequence processing, measurement of linkage disequilibrium, calculation of time to most recent common ancestor, and data conversion/manipulation. Significant extension of the smgf.org website. Architecture and implementation of core package hierarchy in Java, JSP, SQL and HTML.
  • Skills used: algorithm and data structure design, discrete mathematics, statistics, combinatorics, parallel programming, optimization, technical writing. 
  • Leadership: Technical leadership for a team of 7 other people, including four other bioinformaticists. Advising of mathematical/statistical aspects of all research projects.
Software Engineer, ECONZ (www.econz.co.nz), Auckland, New Zealand, 2001
  • Responsibilities: Software development and support for a large call-center and job-tracking application used by the Automobile Association of New Zealand and the Royal Automobile Club of Queensland 
Software Engineer, Adis Press (Wolters-Kluwer), Auckland, New Zealand, 1998-1999
  • Responsibilities: Developed software tools to transform SGML documents between different schemata 
Software Engineer, The NumberWorks math academies, Auckland, New Zealand, 1995
  • Responsibilities: Wrote extensive libraries for rapid development of interactive educational software

Education History

Postdoctoral Research, Harvard Medical School, June 2011 - August 2012
  • Continuation of PhD research
Ph.D. in Computer Science and Computational Biology, MIT, June 2011
  • PhD thesis: Whole-organism integrative expressome for C. elegans enables in silico study of developmental regulation.  [recent poster summarizing research]
    Short abstract:
     The C. elegans nematode has been extensively studied as a model organism 
    since the 1970s, and is the only organism for which the complete cell division tree and the genome are both available. These two datasets were integrated with a number of other datasets available at WormBase.org, such as the anatomy ontology, gene expression profiles extracted from 8000 peer-reviewed papers, and metadata about each gene, to produce the first ever whole-organism, cell-resolution map of gene expression across the entire developmental timeline of the organism, with the goal to find genomic features that regulate cell division and tissue differentiation. Contingency testing was performed to find correlations between thousands of gene attributes (e.g. the presence or absence of a specific 8-mer in the 3' UTR, the GC-content of the sequence upstream of the transcriptional start site, etc.) and thousands of cell attributes (e.g. whether cells that express specific genes die through apoptosis, whether cells become neurons or not, whether cells move in the anterior or posterior direction after division). The resulting database of contingency test scores allow us to quickly ask a large number of biologically-interesting questions, like, "Does the length of introns of expressed genes increase across the developmental timeline?"; "Across what period of development and in which cell types is this specific gene most active?"; "Do regulatory motifs exist that switch on or off genes in whole subtrees of the cell pedigree?"; "Which genes are most strongly implicated in apoptosis?", etc. This whole-organism expressome enables direct and powerful in silico analysis of development.
Graduate of inaugural class of Singularity University, summer 2009 (Global Solutions Program, GSP09)
  • Selected as one of 40 in inaugural class from among 1200 applicants
Graduate of HBA (Harvard Beijing Academy) intensive summer Chinese language training program in 3rd year Chinese, summer 2008
  • Completed 4.5 years of Harvard Chinese syllabus "on the side" in 2.5 years, including HBA summer program, while working on my PhD in CS at MIT
B.Sc.(Hons), Computer Science, University of Auckland, New Zealand, 2000
  • Achievement: 1st Class Honors
  • Research: Neural networks; successful construction of a hierarchical network-of-networks for online handwriting recognition.
B.Sc., Computer Science, University of Auckland, New Zealand, 1999
  • Research: Optimization of computer graphics algorithms; finding heuristic approximations to NP-hard and NP-complete problems. (Found fast heuristics for Traveling Salesman and Hamilton Cycle problems.)

Awards
  • TED Fellowship, TED 2011 ("The Rediscovery of Wonder"), Long Beach, CA, USA. [Press release] [Fast Company interview] [Directory] [Profile] "Founded in January 2009, the TED Fellows program handpicks world-changing innovators from around the globe, and brings them to the TED stage – literally and figuratively – to raise international awareness of their remarkable work... The Fellows program helps amplify the impact of each Fellow's eye-opening ideas, and we're thrilled to welcome these innovators to the TED community."
  • First in Auckland, South Pacific solo programming contest (1998)
  • First in New Zealand, ACM programming competition (1994). Took first place in this university-level competition as a high school student with two friends the same age.
  • Feast Fellowship, The Feast Conference 2013 (http://feastongood.com). [Blog post] "The Feast convenes the most remarkable entrepreneurs, radicals, doers and thinkers who are revolutionizing the way things work for the betterment of humanity."
  • $25,000 scholarship and selection for the inaugural class of Singularity University (GSP-09) "Our mission is to educate, inspire and empower leaders to apply exponential technologies to address humanity’s grand challenges."
  • Inaugural inductee into the Rangitoto College "Summit Academy -- Distinguished Alumni Hall of Fame" (2011).
  • Best Student Paper Award. RootsTech 2011, Salt Lake City, UT.
  • Best App Idea in Developer Challenge. RootsTech 2011, Salt Lake City, UT.
  • Language awards: Third prize, Chinese speech competition, Harvard 2nd Year Chinese (2008); First prize, Korean Speech Competition, BYUP (2003); First prize, Korean Speech Competition, University of Auckland (1998); Third in Auckland, French Speech Competition, Alliance Française (1994)
  • University of Auckland Science Faculty Postgraduate Study Award (1999)
  • Senior Prize in Computer Science, University of Auckland (1998)
  • Information Technology scholarship, RHE and Associates Ltd. Auckland (1998)
  • Coca-Cola/SPANZ national Bachelor's degree full tuition scholarship (1995)

Selected Publications / Talks

Program Committees / Peer Review

Open Source Software
  • Fast Classpath Scanner -- ultra-fast Java classpath scanner and classpath change detector.
  • Android Multitouch Controller -- utility class that makes it significantly easier to add multitouch input to an Android application. Used by many applications in the Google Play Store.

Selected blog posts


Languages spoken
English, Korean, French and Chinese (all to professional level)

Citizenship
New Zealand citizen; US permanent resident / green card holder (obtained via O-1 / EB-1A)

Recommendations
See an extensive list of recommendations here.